' 
SCIENTIFIC SCORE
Moderately Effective
Based on 44 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of Probiotic Bacteria:Lactobacillus acidophilus (La-14),Bifidobacterium lactis (Bl-04),Bifidobacterium longum (Bl-05)
8 Billion CFU
*
Top Medical Research Studies
9.5
Lactococcus lactis shows promise for T1DM
Oral administration of Lactococcus lactis-expressing heat shock protein 65 and tandemly repeated IA2P2 prevents type 1 diabetes in NOD mice.
High relevance for autoimmune research
We investigated the potential of Lactococcus lactis, a safe bacterial strain, to deliver protective proteins for preventing type 1 diabetes (T1DM) in NOD mice. Our study used two specially engineered strains that expressed a specific protein.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
Read More
9
Lactobacillus acidophilus shows promise in autoimmune management
New Lactobacillus acidophilus isolates reduce the release of leptin by murine adipocytes leading to lower interferon-gamma production.
High relevance for autoimmune treatment
We explored how specific Lactobacillus acidophilus strains can impact autoimmune disorders by reducing leptin production in mice. In our study, we compared the effects of CBA4P and other lactobacilli on adipocytes from mice sensitive to Th1 immune diseases.
Results showed that CBA4P significantly lowered leptin levels and inhibited the activation of immune lymphocytes in the SJL mouse strain. This suggests that CBA4P might help manage Th1-related inflammatory conditions, representing a potentially valuable probiotic option for autoimmune control.
Results showed that CBA4P significantly lowered leptin levels and inhibited the activation of immune lymphocytes in the SJL mouse strain. This suggests that CBA4P might help manage Th1-related inflammatory conditions, representing a potentially valuable probiotic option for autoimmune control.
Read More
9
BD400 reduces RA symptoms effectively
BD400 protects from collagen-induced arthritis through histidine metabolism.
Highly relevant to RA treatment
We studied the effects of BD400 in a collagen-induced arthritis rat model, aiming to understand if it could delay rheumatoid arthritis (RA). Through monitoring arthritis signs, measuring gut health, and assessing immune responses, we found that BD400 significantly reduced swelling and clinical scores in the rats.
Additionally, it positively impacted the gut microbiota and metabolite levels, particularly through histidine metabolism. This led to a decrease in inflammation and improved intestinal barrier function, hinting at BD400's potential as a preventive treatment for RA.
Additionally, it positively impacted the gut microbiota and metabolite levels, particularly through histidine metabolism. This led to a decrease in inflammation and improved intestinal barrier function, hinting at BD400's potential as a preventive treatment for RA.
Read More
Most Useful Reviews
9.5
Restored digestion
After suffering from an autoimmune disorder, my mother experienced severe dysbiosis post-covid. Pharmaceuticals failed to help, but these capsules significantly restored her digestive health from the first days of use.
Read More
8.3
Improved environment
After childbirth, I used advanced ferrochel to improve my ferritin levels, along with these probiotics. They effectively improved my intestinal environment and have shown excellent results for my autoimmune disorder.
Read More
8.3
Balanced flora
Probiotics are essential for maintaining my oral and intestinal flora balance, crucial for managing my autoimmune disorder. When I run out, I can certainly tell the difference.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 44 Researches
8
- All Researches
9.5
Lactococcus lactis shows promise for T1DM
Oral administration of Lactococcus lactis-expressing heat shock protein 65 and tandemly repeated IA2P2 prevents type 1 diabetes in NOD mice.
High relevance for autoimmune research
We investigated the potential of Lactococcus lactis, a safe bacterial strain, to deliver protective proteins for preventing type 1 diabetes (T1DM) in NOD mice. Our study used two specially engineered strains that expressed a specific protein.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
Read More
9
Probiotic IRT5 reduces diabetes effects
Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics.
Relevant for diabetes research
We examined how a special probiotic mix, known as IRT5, affects autoimmune diabetes in non-obese diabetic (NOD) mice. Administered frequently over 36 weeks, this combination not only reduced diabetes incidence but also lowered insulitis scores and increased insulin-producing β-cell mass.
Additionally, IRT5 improved gut health and changed the makeup of immune cells in the pancreas and intestines. While some immune responses stayed the same, the shift towards more gut-focused regulatory T cells suggests it could be a promising treatment for type 1 diabetes.
Additionally, IRT5 improved gut health and changed the makeup of immune cells in the pancreas and intestines. While some immune responses stayed the same, the shift towards more gut-focused regulatory T cells suggests it could be a promising treatment for type 1 diabetes.
Read More
9
Synbiotics improve rheumatoid arthritis symptoms
Synbiotic supplementation and the effects on clinical and metabolic responses in patients with rheumatoid arthritis: a randomised, double-blind, placebo-controlled trial.
High relevance; significant findings
We investigated how synbiotic supplementation affects patients with rheumatoid arthritis (RA). In an 8-week, randomized, double-blind trial involving 54 participants, we compared the outcomes of those taking synbiotic capsules with a placebo group.
After the trial, those who received synbiotics showed a significant drop in inflammation markers and pain levels. Additionally, improvements were observed in insulin resistance and overall metabolic responses.
These findings suggest that synbiotics might benefit individuals managing RA by reducing inflammation and enhancing metabolic health.
After the trial, those who received synbiotics showed a significant drop in inflammation markers and pain levels. Additionally, improvements were observed in insulin resistance and overall metabolic responses.
These findings suggest that synbiotics might benefit individuals managing RA by reducing inflammation and enhancing metabolic health.
Read More
9
Lactobacillus acidophilus shows promise in autoimmune management
New Lactobacillus acidophilus isolates reduce the release of leptin by murine adipocytes leading to lower interferon-gamma production.
High relevance for autoimmune treatment
We explored how specific Lactobacillus acidophilus strains can impact autoimmune disorders by reducing leptin production in mice. In our study, we compared the effects of CBA4P and other lactobacilli on adipocytes from mice sensitive to Th1 immune diseases.
Results showed that CBA4P significantly lowered leptin levels and inhibited the activation of immune lymphocytes in the SJL mouse strain. This suggests that CBA4P might help manage Th1-related inflammatory conditions, representing a potentially valuable probiotic option for autoimmune control.
Results showed that CBA4P significantly lowered leptin levels and inhibited the activation of immune lymphocytes in the SJL mouse strain. This suggests that CBA4P might help manage Th1-related inflammatory conditions, representing a potentially valuable probiotic option for autoimmune control.
Read More
9
Bifidobacterium longum aids thyroid function
Probiotic Bifidobacterium longum supplied with methimazole improved the thyroid function of Graves' disease patients through the gut-thyroid axis.
High relevance due to findings
Our study investigated how Bifidobacterium longum, paired with methimazole, affects thyroid function in Graves' disease patients. Over six months, we divided participants into distinct treatment groups.
While methimazole alone improved thyroid health markers, it didn’t significantly lower the thyrotropin receptor antibody, an important indicator of potential disease recurrence. On the other hand, those receiving Bifidobacterium longum along with methimazole showed notable improvements, with TRAb levels returning to normal.
This suggests that probiotics might positively influence thyroid function by altering gut microbiota and metabolites, linking the gut and thyroid effectively.
While methimazole alone improved thyroid health markers, it didn’t significantly lower the thyrotropin receptor antibody, an important indicator of potential disease recurrence. On the other hand, those receiving Bifidobacterium longum along with methimazole showed notable improvements, with TRAb levels returning to normal.
This suggests that probiotics might positively influence thyroid function by altering gut microbiota and metabolites, linking the gut and thyroid effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Restored digestion
After suffering from an autoimmune disorder, my mother experienced severe dysbiosis post-covid. Pharmaceuticals failed to help, but these capsules significantly restored her digestive health from the first days of use.
8.3
Improved environment
After childbirth, I used advanced ferrochel to improve my ferritin levels, along with these probiotics. They effectively improved my intestinal environment and have shown excellent results for my autoimmune disorder.
8.3
Balanced flora
Probiotics are essential for maintaining my oral and intestinal flora balance, crucial for managing my autoimmune disorder. When I run out, I can certainly tell the difference.
8.8
Works well
I ordered it in the cold weather and found it effective. While it may not be the strongest, it certainly aids in tackling intestinal viruses, which is beneficial for autoimmune disorders.
9
Copes with imbalances
In cases of intestinal dysfunction related to my autoimmune disorder, I take one capsule daily. It helps alleviate imbalances like bloating and flatulence, making a significant difference in my wellbeing.
